Hydrocephalus in Suckling Rats Infected Intracerebrally with Mouse Hepatitis Virus, MHV‐A59
Identifieur interne : 001725 ( Main/Exploration ); précédent : 001724; suivant : 001726Hydrocephalus in Suckling Rats Infected Intracerebrally with Mouse Hepatitis Virus, MHV‐A59
Auteurs : Norio Hirano [Japon] ; Naoaki Goto [Japon] ; Tetsuo Ogawa [Japon] ; Katsuhiko Ono [Japon] ; Toshiaki Murakami [Japon] ; Kosaku Fujiwara [Japon]Source :
- Microbiology and Immunology [ 0385-5600 ] ; 1980-09.
English descriptors
- Teeft :
- Acta neuropathol, Animals inoculated, Anomaly, Brain days, Brain lesions, Cancer inst, Cell cultures, Cerebral cortex, Cerebral lesions, Cerebrospinal fluid, Encephalitis, Extensive destruction, Fujiwara, Gesamte virusforsch, Hamster, Hepatitis, Hepatitis virus, High frequency, Hirano, Hydrocephalus, Immunofluorescence, Inoculated, Inoculation, Intracerebral inoculation, Lesion, Measles virus, Mouse, Mouse cell line, Mouse hepatitis virus, Mouse leukemia, Murine virus, Neuron, Numerous neurons, Oligodendroglia cells, Present study, Rat, Reovirus type, Respiratory infection, Rhesus monkeys, Sialodacryoadenitis virus, Subacute encephalitis, Suckling, Suckling rats, Survivors inoculated, Uninfected control, Virus, Virus antigen, Virus assay, Virus titer, Wistar rats.
Abstract
After intracerebral inoculation of mouse hepatitis virus, MHV‐A59 strain, into 3‐ to 5‐day‐old Wistar rats, some survivors at 14 days postinoculation (p.i.) were found to lack the cerebral cortex and to have an accumulation of a considerable amount of cerebrospinal fluid. The virus titer in the brain increased exponentially after inoculation, reaching a maximum 4 to 6 days p.i. when immunofluorescence revealed virus‐specific antigen within neurons in the cerebral cortex. A small amount of infectious virus was also detectable 14 days p.i. when the cerebral anomaly was evident. This brain malformation causing hydrocephalus was due to cerebral damage by viral infection.
Url:
DOI: 10.1111/j.1348-0421.1980.tb02887.x
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000408
- to stream Istex, to step Curation: 000388
- to stream Istex, to step Checkpoint: 000832
- to stream Main, to step Merge: 001754
- to stream Main, to step Curation: 001725
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Hydrocephalus in Suckling Rats Infected Intracerebrally with Mouse Hepatitis Virus, MHV‐A59</title><author><name sortKey="Hirano, Norio" sort="Hirano, Norio" uniqKey="Hirano N" first="Norio" last="Hirano">Norio Hirano</name></author><author><name sortKey="Goto, Naoaki" sort="Goto, Naoaki" uniqKey="Goto N" first="Naoaki" last="Goto">Naoaki Goto</name></author><author><name sortKey="Ogawa, Tetsuo" sort="Ogawa, Tetsuo" uniqKey="Ogawa T" first="Tetsuo" last="Ogawa">Tetsuo Ogawa</name></author><author><name sortKey="Ono, Katsuhiko" sort="Ono, Katsuhiko" uniqKey="Ono K" first="Katsuhiko" last="Ono">Katsuhiko Ono</name></author><author><name sortKey="Murakami, Toshiaki" sort="Murakami, Toshiaki" uniqKey="Murakami T" first="Toshiaki" last="Murakami">Toshiaki Murakami</name></author><author><name sortKey="Fujiwara, Kosaku" sort="Fujiwara, Kosaku" uniqKey="Fujiwara K" first="Kosaku" last="Fujiwara">Kosaku Fujiwara</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:1413931651F924D55190F0105E5B6219FD2FFA77</idno><date when="1980" year="1980">1980</date><idno type="doi">10.1111/j.1348-0421.1980.tb02887.x</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-TGQXTJ40-8/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000408</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000408</idno><idno type="wicri:Area/Istex/Curation">000388</idno><idno type="wicri:Area/Istex/Checkpoint">000832</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000832</idno><idno type="wicri:doubleKey">0385-5600:1980:Hirano N:hydrocephalus:in:suckling</idno><idno type="wicri:Area/Main/Merge">001754</idno><idno type="wicri:Area/Main/Curation">001725</idno><idno type="wicri:Area/Main/Exploration">001725</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Hydrocephalus in Suckling Rats Infected Intracerebrally with Mouse Hepatitis Virus, MHV‐A59</title><author><name sortKey="Hirano, Norio" sort="Hirano, Norio" uniqKey="Hirano N" first="Norio" last="Hirano">Norio Hirano</name><affiliation></affiliation><affiliation wicri:level="3"><country>Japon</country><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName><wicri:orgArea>Department of Veterinary Pathology, Faculty of Agriculture, University of Tokyo, Bunkyo‐ku, 113</wicri:orgArea></affiliation></author><author><name sortKey="Goto, Naoaki" sort="Goto, Naoaki" uniqKey="Goto N" first="Naoaki" last="Goto">Naoaki Goto</name><affiliation></affiliation><affiliation wicri:level="3"><country>Japon</country><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName><wicri:orgArea>Department of Veterinary Pathology, Faculty of Agriculture, University of Tokyo, Bunkyo‐ku, 113</wicri:orgArea></affiliation></author><author><name sortKey="Ogawa, Tetsuo" sort="Ogawa, Tetsuo" uniqKey="Ogawa T" first="Tetsuo" last="Ogawa">Tetsuo Ogawa</name><affiliation></affiliation><affiliation wicri:level="3"><country>Japon</country><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName><wicri:orgArea>Department of Veterinary Pathology, Faculty of Agriculture, University of Tokyo, Bunkyo‐ku, 113</wicri:orgArea></affiliation></author><author><name sortKey="Ono, Katsuhiko" sort="Ono, Katsuhiko" uniqKey="Ono K" first="Katsuhiko" last="Ono">Katsuhiko Ono</name><affiliation></affiliation><affiliation wicri:level="3"><country>Japon</country><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName><wicri:orgArea>Department of Veterinary Pathology, Faculty of Agriculture, University of Tokyo, Bunkyo‐ku, 113</wicri:orgArea></affiliation></author><author><name sortKey="Murakami, Toshiaki" sort="Murakami, Toshiaki" uniqKey="Murakami T" first="Toshiaki" last="Murakami">Toshiaki Murakami</name><affiliation></affiliation><affiliation wicri:level="3"><country>Japon</country><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName><wicri:orgArea>Department of Veterinary Pathology, Faculty of Agriculture, University of Tokyo, Bunkyo‐ku, 113</wicri:orgArea></affiliation></author><author><name sortKey="Fujiwara, Kosaku" sort="Fujiwara, Kosaku" uniqKey="Fujiwara K" first="Kosaku" last="Fujiwara">Kosaku Fujiwara</name><affiliation></affiliation><affiliation wicri:level="3"><country>Japon</country><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName><wicri:orgArea>Department of Veterinary Pathology, Faculty of Agriculture, University of Tokyo, Bunkyo‐ku, 113</wicri:orgArea></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Microbiology and Immunology</title><title level="j" type="alt">MICROBIOLOGY AND IMMUNOLOGY</title><idno type="ISSN">0385-5600</idno><idno type="eISSN">1348-0421</idno><imprint><biblScope unit="vol">24</biblScope><biblScope unit="issue">9</biblScope><biblScope unit="page" from="825">825</biblScope><biblScope unit="page" to="834">834</biblScope><biblScope unit="page-count">10</biblScope><date type="published" when="1980-09">1980-09</date></imprint><idno type="ISSN">0385-5600</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0385-5600</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Acta neuropathol</term><term>Animals inoculated</term><term>Anomaly</term><term>Brain days</term><term>Brain lesions</term><term>Cancer inst</term><term>Cell cultures</term><term>Cerebral cortex</term><term>Cerebral lesions</term><term>Cerebrospinal fluid</term><term>Encephalitis</term><term>Extensive destruction</term><term>Fujiwara</term><term>Gesamte virusforsch</term><term>Hamster</term><term>Hepatitis</term><term>Hepatitis virus</term><term>High frequency</term><term>Hirano</term><term>Hydrocephalus</term><term>Immunofluorescence</term><term>Inoculated</term><term>Inoculation</term><term>Intracerebral inoculation</term><term>Lesion</term><term>Measles virus</term><term>Mouse</term><term>Mouse cell line</term><term>Mouse hepatitis virus</term><term>Mouse leukemia</term><term>Murine virus</term><term>Neuron</term><term>Numerous neurons</term><term>Oligodendroglia cells</term><term>Present study</term><term>Rat</term><term>Reovirus type</term><term>Respiratory infection</term><term>Rhesus monkeys</term><term>Sialodacryoadenitis virus</term><term>Subacute encephalitis</term><term>Suckling</term><term>Suckling rats</term><term>Survivors inoculated</term><term>Uninfected control</term><term>Virus</term><term>Virus antigen</term><term>Virus assay</term><term>Virus titer</term><term>Wistar rats</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract">After intracerebral inoculation of mouse hepatitis virus, MHV‐A59 strain, into 3‐ to 5‐day‐old Wistar rats, some survivors at 14 days postinoculation (p.i.) were found to lack the cerebral cortex and to have an accumulation of a considerable amount of cerebrospinal fluid. The virus titer in the brain increased exponentially after inoculation, reaching a maximum 4 to 6 days p.i. when immunofluorescence revealed virus‐specific antigen within neurons in the cerebral cortex. A small amount of infectious virus was also detectable 14 days p.i. when the cerebral anomaly was evident. This brain malformation causing hydrocephalus was due to cerebral damage by viral infection.</div></front></TEI><affiliations><list><country><li>Japon</li></country><region><li>Région de Kantō</li></region><settlement><li>Tokyo</li></settlement></list><tree><country name="Japon"><region name="Région de Kantō"><name sortKey="Hirano, Norio" sort="Hirano, Norio" uniqKey="Hirano N" first="Norio" last="Hirano">Norio Hirano</name></region><name sortKey="Fujiwara, Kosaku" sort="Fujiwara, Kosaku" uniqKey="Fujiwara K" first="Kosaku" last="Fujiwara">Kosaku Fujiwara</name><name sortKey="Goto, Naoaki" sort="Goto, Naoaki" uniqKey="Goto N" first="Naoaki" last="Goto">Naoaki Goto</name><name sortKey="Murakami, Toshiaki" sort="Murakami, Toshiaki" uniqKey="Murakami T" first="Toshiaki" last="Murakami">Toshiaki Murakami</name><name sortKey="Ogawa, Tetsuo" sort="Ogawa, Tetsuo" uniqKey="Ogawa T" first="Tetsuo" last="Ogawa">Tetsuo Ogawa</name><name sortKey="Ono, Katsuhiko" sort="Ono, Katsuhiko" uniqKey="Ono K" first="Katsuhiko" last="Ono">Katsuhiko Ono</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001725 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001725 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:1413931651F924D55190F0105E5B6219FD2FFA77
|texte= Hydrocephalus in Suckling Rats Infected Intracerebrally with Mouse Hepatitis Virus, MHV‐A59
}}
| This area was generated with Dilib version V0.6.33. |  |